NONMETASTATIC TUMORS OF THE ADRENAL GLANDS IN CANCER PATIENTS
- Authors: Spiridonov D.A.1, Proscyrakova O.V.2, Andreev V.A.2
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Affiliations:
- Voronezh State Medikal Univesite named after N.N. Burdenko
- Voronezh Stаte Medical Univesity named after N.N. Burdenko
- Issue: Vol 12 (2023): MATERIALS OF THE XIX INTERNATIONAL BURDENKOVO SCIENTIFIC CONFERENCE APRIL 20-22, 2023
- Pages: 262-263
- Section: Онкология
- URL: https://www.new.vestnik-surgery.com/index.php/2415-7805/article/view/8643
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Abstract
Relevance. The life expectancy of cancer patients depends entirely on full-fledged dispensary observation, where key attention is paid to the early detection of relapses and metastases of the primary malignant focus. Today, the interest of doctors of all specialties in neoplasms of the adrenal glands is growing, especially in patients with a burdened oncological history. However, the data regarding metastatic adrenal cancer in most cases are based on the results of autopsy. This dictates the need to update the results of an intravital study of the histological material of adrenal neoplasms in patients, which will make it possible to develop tactics for the management and subsequent treatment of patients. Materials and methods. The medical documentation of patients with a history of malignant neoplasms was studied, in which, during the planned dispensary observation, ultrasound and then MRI (CT) of the abdominal cavity and retroperitoneal space revealed the presence of tumors of the adrenal glands. Material for pathomorphological examination was obtained by performing a biopsy of the tumor and laparoscopic adrenalectomy. The discussion of the results. Histological examination of the obtained material made it possible to identify benign and malignant (metastatic) lesions.
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Relevance. Metastases to the adrenal glands can be solitary, without damage to other organs [1]. This often serves as an indicator of the progression of the disease [2]. Determination of the nature of the detected adrenal tumor in oncological patients is considered mandatory [2].
The purpose of the study. To evaluate the occurrence of non-metastatic adrenal neoplasms in patients with a burdened oncological history.
Material and methods. The conclusions of histological studies of adrenal tumors of patients of the III clinical group who were radically treated for malignant neoplasms of non-adrenal localization and underwent routine medical examination were analyzed in detail. The absence of hormonal activity of neoplasms was established by laboratory studies.
Results. Nonmetastatic neoplasms (adenomas, cysts, hyperplastic foci) were detected in 73% of patients, metastatic in 27%. After radical treatment of breast cancer (N=20) and uterine body cancer (N=3), all adrenal tumors turned out to be benign. The greatest number of metastases to the adrenal glands was found in lung cancer (13%), kidney (11%), colon (6%), stomach (5%), skin melanoma (4%).
About the authors
Dmitriy Andreevich Spiridonov
Voronezh State Medikal Univesite named after N.N. Burdenko
Author for correspondence.
Email: vova-2001@yandex.ru
ORCID iD: 0009-0002-3557-0727
Department of Oncology, resident
Russian Federation, Voronezh, 10, Studencheskay street, Russia, 3940000Olga Vladimirovna Proscyrakova
Voronezh Stаte Medical Univesity named after N.N. Burdenko
Email: rebrova_1795@mail.ru
ORCID iD: 0009-0007-6622-1104
Depatment of oncology, resident
Russian Federation, Voronezh, 10, Studencheskay street, Russia, 3940000Vladimir Alekseevich Andreev
Voronezh Stаte Medical Univesity named after N.N. Burdenko
Email: yzel.nauka@gmail.com
ORCID iD: 0009-0005-6833-8440
Faculty of Medicine, student
Russian Federation, Voronezh, 10, Studencheskay street, Russia, 3940000References
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