THE COMPARATIVE ANALYSIS OF FUNCTIONAL INDICES IN PATIENTS WITH OSTEOARTHRITIS AND COMORBID OBESITY
- Authors: Абакумова С.А.1, Korneev R.V.2
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Affiliations:
- Voronezh State Medical University named after Nikolai Nilovich Burdenko
- VSMU um N.N Burdenko
- Issue: Vol 10 (2021): Материалы XVII Международной Бурденковской научной конференции 22-24 апреля 2021 года
- Pages: 548-548
- Section: Medicine without frontiers
- URL: https://www.new.vestnik-surgery.com/index.php/2415-7805/article/view/6551
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Abstract
Objectives: assessment of knee joints in patients with osteoarthritis and obesity
Methods: The study included 40 patients with osteoarthritis in the age group from 45 to 65 years, 80% women and 20% men. The patients were divided into 2 groups. In the first group of patients, in addition to OA, concomitant obesity was diagnosed. In group 2, patients suffered from osteoarthritis
Results: The result of the analysis was that the people who were included in the second group differed significantly from patients with OA and concomitant obesity.
Conclusion: in patients with OA and without comorbid obesity, there was an increase in the functional activity of the knee joints and a decrease in pain according to the VAS, compared with patients with OA and concomitant obesity.
Full Text
The comparative analysis of functional indices in patients with osteoarthritis and comorbid obesity
Background. Obesity is one of the most important risk factors for the manifestation and further deterioration of osteoarthritis (OA). It is well known the relationship between the risk of association and progression of knee osteoarthritis and level of BMI [1, 2, 3].
Objectives. To analyze the limitations physical activity of patients with osteoarthritis (OA) in combination with obesity.
Material and method. 40 patients with OA with the mean age 52.3±10.2 were included in the trial. 80% females and 20% males participated in the study. The diagnosis of osteoarthritis was established according to the criteria of Kellgren and Lawrence. The duration of OA is from 5 to 10 years. Inclusion criteria: informed consent of participation in the study, age over 42 years, mainly knee joint damage (knee OA), The stage according to X-ray is II, no comorbid liver and kidney diseases in the stage of functional decompensation, absent of previous intra-articular injections at least 3 months before the trial. The patients were classified into 2 groups. Patients with OA of group 1 (n=40) had comorbid obesity. In group 2 (control) (n=40), patients had only OA. Functional activity in the compared groups was assessed using a visual analog scale (pain on VAS), as well as the Lequesne and WOMAC functional indices.
Results. As a result of the comparative analysis, the values of the pain on VAS, WOMAC and Lequesne in group 2 were 41±1.51 (p<0.001), 89.9±1.49 (p<0.001) and 9.75±0.28 (p<0.001), respectively, and significantly differed from patients with OA and concomitant obesity. The values of the studied parameters in group 1 of patients exceeded the values in the control group by an average of 15-20%.
Conclusion In patients with osteoarthritis in combination with obesity, there was a decrease in the functional activity of the knee joints and increased pain on VAS compared to patients with OA without a comorbid condition.
References: 1. Tukker A.,Visscher T.L.S., Picavet H.S.J. Overweight and health problems of the lower extremities: osteoarthritis, pain and disability.
Public Health Nutr 2007;12:3359-368.
2. Zhang Y., Jordan J.M. Epidemiology of Osteoarthritis. Clin Geriatr Med 2010;26:3:355-369.
3. Manek Nisha J., Hart D., Spector T. D., MacGredor Alexander J. The association of body mass index and osteoarthritis of the knee joint: an examination of genetic and environmental influence. Arthrit Rheum 2003;48:4:1024-1029.
About the authors
София Александровна Абакумова
Voronezh State Medical University named after Nikolai Nilovich Burdenko
Author for correspondence.
Email: abakumovasof@yandex.ru
ORCID iD: 0000-0002-2273-8474
Russian Federation
Roman Vyacheslavovich Korneev
VSMU um N.N Burdenko
Email: on.romka@yandex.ru
ORCID iD: 0000-0002-7697-6902
References
- Tukker A.,Visscher T.L.S., Picavet H.S.J. Overweight and health problems of the lower extremities: osteoarthritis, pain and disability.
- Public Health Nutr 2007;12:3359-368.
- Zhang Y., Jordan J.M. Epidemiology of Osteoarthritis. Clin Geriatr Med 2010;26:3:355-369.
- Manek Nisha J., Hart D., Spector T. D., MacGredor Alexander J. The association of body mass index and osteoarthritis of the knee joint: an examination of genetic and environmental influence. Arthrit Rheum 2003;48:4:1024-1029.
- Reijman M., Pols H.A., Bergink A.P. et al. Body mass index associated with onset and progression of Osteoarthritis of the knee but not of the hip. The Rotterdam Study. Ann Rheum Dis 2007;66:158-162.
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